This website uses cookies to ensure you have the best experience. Learn more

Myasthenia Gravis Essay

1183 words - 5 pages

Introduction

Myasthenia gravis is an autoimmune disease in which antibodies are produced that block or destroy the nicotine acetylcholine receptors at the postsynaptic membrane, causing muscle weakness and fatigue (Pendleton & Schultz-Krohn, 2006). Myasthenia gravis can occur at any age but onset usually occurs at an earlier age in women than in men. In the United States, there are about 14.2 cases of myasthenia gravis per one million people (Pendleton & Schultz-Krohn, 2006).
Myasthenia gravis will be discussed in this paper according to the following: etiology, signs and symptoms, pathology and the progression of myasthenia gravis, diagnosis, prognosis, medical ...view middle of the document...

Post-synaptic sites may show a decrease in acetylcholine response because of a mutation in receptor subunits, a deficiency in plectrin, receptor clustering due to rapsyn mutations, or an increased response to acetylcholine resulting in slow-channel syndrome (Keesy, 2004, p. 485). 75-90% of patients are seropositive for acetylcholine receptor antibodies that bind to acetylcholine receptors. 10-25% of seronegative patients have been found to carry a different antibody, now identified as anti-muscle specific kinase antibodies, that bind to tyrosine kinase receptors on the muscle side of the neuromuscular junction (Keesy, 2004, p. 486).
Myasthenia gravis affects people in many different ways and it is important to know that every patient may present with different signs and symptoms of the disease. At one time the individual may function normally, and at another time he or she may experience severe loss of strength. Most patients with the disease begin to have symptoms of weakness in muscles that control the eye or eyelids. The symptoms range from difficulty in eye motion resulting in double vision or droopy eyelids on one or both sides. The symptoms may progress in any number of ways. 10 to 20% of people who present with ocular symptoms have symptoms remain long term and never have symptoms progress to other parts of their body (Goodman et al., 2003).
The other group of patients with ocular symptoms may experience spontaneous improvement, however within the first year of diagnosis there is a chance that they will experience some kind of fluctuation of the illness. These patients may have symptoms other than ocular manifestations such as oral symptoms including difficulties with swallowing, chewing, speaking, smiling, and breathing (Goodman et al., 2003). Within the first year, patients with ocular symptoms may experience weakness and numbness throughout the body with feelings of heaviness, muscular spasm, or loss of limb control. Limb weakness often presents asymmetrically. Myasthenia gravis is in itself painless, but the strain of supporting weak limbs or the neck can be painful. Additionally, patients with muscle weakness may experience a sense of loss of balance (Goodman et al. , 2003).
A diagnosis of myasthenia gravis can have an impact on a person’s daily routines. Patients can experience problems with vision, muscle weakness, and fatigue. They may also have difficulty swallowing, chewing, and breathing (Leonardi, Raggi, Antozzi, Confalonieri, Maggi, Cornelio, & Mantegazza, 2009). As mentioned, myasthenia gravis is a fluctuating disorder and repetitive muscle movement can cause a decrease in muscle strength and endurance by the end of the day (Pendleton & Schultz-Krohn, 2006, p. 943).
According to Adams (2008), there are other situations that can intensify the resulting dysfunction of myasthenia gravis, such as stress, pregnancy, heat, and certain medications. Some patients with myasthenia gravis...

Other assignments on Myasthenia Gravis

Economy Effect Of Marijuana Essay

277 words - 2 pages Modern American History by Alan Renga 2nd Mid Term! You will be given 3 Short Essay questions and 20 Multiple Choice questions deriving from this list! 80 points total! The 1920s Warren Harding then Calvin Coolidge Tea Pot Dome 1st Red Scare Immigration Restriction, Sacco and Vanzetti Langston Hughes, Marcus Garvey, KKK Prosperity, advertising Prohibition, Al Capone Flappers, Clara Bow, Rudolph Valentino Babe Ruth, Jack Dempsey

The Vc Shakeout Essay

2033 words - 9 pages ECONOMY 26 Luring a big firm to town is not the secret to job growth DEFEND YOUR RESEARCH 30 Are morning people wired for success? VISION STATEMENT 32 The social web’s east-west divide COLUMN 38 Warren Bennis looks back on his surprising path to fame New Thinking, Research in Progress hbr.org New Thinking, Research in Progress hbr.org FIRST The VC Shakeout Venture capital hasn’t worked for a decade and must be radically

Hospitals Paper

6014 words - 25 pages I hope to provide in this paper a comprehensive understanding for what the term “hospital” has become. Hospitals are an extremely complex system that man has created and shaped and reshaped throughout history. My goal in writing and researching this paper will be to provide those who read it a clear understanding on how the hospital system got to where it is today, and to shed some light on the many organizations that affiliate with and

Course Syllabus

2610 words - 11 pages [pic] COURSE SYLLABUS Semester: Fall, Year: 2012  College Mission Statement Richard J. Daley College provides high-quality education which leads to academic success, career development, and personal enrichment that fulfill diverse community needs. Mathematics Department Mission Statement Our mission is to deliver excellent service and to provide learning opportunities by offering a wide range of mathematics courses, which will help our

Management

1477 words - 6 pages Boeing Management Planning Heather Oetzel MGT 330 October 22, 2012 Joe Cheng Abstract Boeing is known as “the world’s leading aerospace company and the largest manufacturer of commercial jetliner and military aircraft combined ("The Boeing Company: About Us", 2012). Every company uses different types of management techniques including how the planning function of management is used. Planning allows organizations to develop how the

Assisted Suicide

1015 words - 5 pages Should physician-assisted suicide be legal? While I believe if one chooses to end his or own life through physician assistance for reasons that they chose, the choice should be up to the individual. Physician-assisted suicide should be at one's discretion. “Assisted Suicide, also called Voluntary Euthanasia, is currently a contentious issue in many countries. Because Euthanasia is legal in a few modern democracies: the Netherlands, Belgium

Tanglewood Case 1

797 words - 4 pages Tanglewood’s staffing strategy requires the organization to make key decisions about the acquisition, deployment, and retention of the organization’s workforce. In order to accomplish this, Tanglewood’s must make thirteen decisions regarding its staffing levels and its staffing quality. One of the first decisions that Tanglewood needs to choose is to acquire or develop talent. Tanglewood should try to develop their current talent because one

Nnnnn

1391 words - 6 pages Есе по въпроса: Кои от всички „действащи” лица могат да се разглеждат като морално отговорни и в какво именно? по казуса Форд „Пинто” Корпоративните злодеяния са нанесли повече вреди на обществото от всички улични престъпления взети заедно. Според данни на ФБР сумата от уличните престъпления възлиза на $3.8 млрд. годишно, а загубите от корпоративните измами между $100 млрд. и $400 млрд. годишно

The Penis

1052 words - 5 pages The short story ”The Penis” is written by Hanif Kureishi. The short story is about a penis, which has been separated from its owner Doug, who we hear from later on. At first though we hear about a guy called Alfie who was “a cutter – a hairdresser – and had to get to work”. He is having breakfast with his wife, when she asks him what he did last night, and if he had a good time last night? Alfie can not remember what he did last night, he then

Managed Care Paper

543 words - 3 pages Managed Care and Case Management Care Marvin Lloyd BSHS/402-Case Management 27 August 2012 Virgil Miller Managed Care are techniques employed to help reduce the cost for providing health benefits and a system for improving organizations quality of care

Media

439 words - 2 pages The life expectancy is lower; so people are not kept alive with drugs for decades in a virtual sleep state. There is less state education; so kids don't have it drilled into them that their only goal in life is to make money, at the cost of 'everything' else. The health care is less; so diseases, usually brought by Westerners, kill many more than they do in countries where drug companies can make a fortune from selling medicines that aren't

Similar Documents

Quality Management Essay

1341 words - 6 pages There must be a neural stimulus o There must be calcium in the muscle cells o ATP must be available for energy Q2. Discuss the anatomy/physiology of the pathologic process involved in Myesthenia Gravis. Specifically, focus on how normal anatomy/physiology has been altered to present the disease state. Myasthenia gravis is a potentially serious but treatable organ specific autoimmune disorder characterised by

Case Study

1980 words - 8 pages gravis. This drug, like the edrophonium chloride injection, will make Annie feel stronger. Go back to the flow diagram, look at each stage, and determine how these drugs could work to increase synaptic performance. Upon further research multiple sclerosis is not as qualified in this case as myasthenia gravis which is the autoimmune disease that is affected in the postsynaptic membrane of the neuromuscular junction where acetylcholine isn’t being

Hemodialysis And Peritonial Dialysis Essay

4337 words - 18 pages body, blood cells and plasma are separated, the blood cells are returned while the plasma is collected and frozen to preserve it for eventual use in the manufacture of a variety of medications. The procedure is used to treat a variety of disorders, including those of the immune system, such as Good pasture's syndrome, myasthenia gravis, Guillain-Barre syndrome, lupus, and thrombotic thrombocytopenic purpura. B. PERITONEAL DIALYSIS Peritoneal

Mgt216 Essay

714 words - 3 pages The first ethical issue presented in the ethics game simulation was whether to warn consumers about the contaminated product and what information to provide consumers about the contaminant. The second ethical issue was whether to sell a product that does not meet U.S. safety requirements in a foreign market that has lower safety restrictions. G-BioSport was not required to meet prior approval from the Federal Drug Administration before they